HPV16 refers to human papillomavirus type 16. HPV16 is a high-risk type, low-risk HPV11 virus can cause condyloma acuminatum, high-risk long-term infection may be related to the occurrence of cervical cancer in women. High risk HPV infection causes epithelial cell lesions of genital cancer and cervical cancer, which is the beginning of genital cancer and cervical precancerous cell virus.
HPV16 是指（HPV）人乳头瘤病毒 16 型。HPV 有多种类型，其中低危型 HPV 感染，主要引起生殖器疣（俗称菜花），而高危型 HPV 感染则引起生殖器癌和子宫颈癌上皮细胞病变，此病毒为生殖器癌和子宫颈癌前细胞病毒的开端。HPV16 属于高危型，低危 HPV11 病毒会导致尖锐湿疣，高危长期感染可能与女性宫颈癌的发生有关。
HPV16 refers to human papillomavirus type 16. There are many types of HPV, among which low-risk HPV infection mainly causes genital warts (commonly known as cauliflower), while high-risk HPV infection causes epithelial cell lesions of genital cancer and cervical cancer, which is the beginning of genital cancer and cervical precancerous cell virus. HPV16 is a high-risk type, low-risk HPV11 virus can cause condyloma acuminatum, high-risk long-term infection may be related to the occurrence of cervical cancer in women.
Introduction to virus
HPV16 是 HPV 病毒的一种类型。HPV(人乳头状瘤病毒) 表现为寻常疣、生殖器疣（尖锐湿疣）等症状。 随着性病中尖锐湿疣的发病率急速上升和宫颈癌、肛门癌等的增多，人乳头瘤病毒（hpv）分很多型,其中 HPV16/18 型与宫颈癌有关。
HPV16 is a type of HPV virus. HPV (human papillomavirus) is characterized by verruca vulgaris, genital warts (condyloma acuminatum) and other symptoms. With the rapid increase of the incidence rate of condyloma acuminatum in venereal diseases and the increase of cervical cancer and anal cancer, there are many types of human papillomavirus (HPV), among which HPV16/18 is related to cervical cancer.
按感染部位分类： HPV16 归类为黏膜型病毒
According to the location of infection: HPV16 is classified as mucosal virus
According to carcinogenicity, HPV16 is classified as high risk virus
Biological characteristics of HPV16
人乳头瘤病毒（HPV）是一种属于乳多空病毒科的乳头瘤空泡病毒 A 属，是球形 DNA 病毒，能引起人体皮肤黏膜的鳞状上皮增殖。已分离出 130 多种，不同的型别引起不同的临床表现。
Human papillomavirus (HPV) is a kind of papillomavirus a belonging to the family lactaviridae. It is a spherical DNA virus, which can cause the proliferation of squamous epithelium of human skin and mucosa. More than 130 types have been isolated, and different types cause different clinical manifestations.
HPV16 阳性是感染了人类乳头瘤病毒，HPV 可引起人类良性的肿瘤和疣，如生长在生殖器官附近皮肤和粘膜上的人类寻常疣、尖锐湿疣以及生长在粘膜上的乳头状瘤。HPV 在皮肤癌和其它解剖部分的肿瘤似乎起决定作用。口腔良性赘生物和癌前病变，皮肤鳞状细胞癌组织中可发现 HPV-11、16、18 型 DNA。另外，尖锐湿疣与 HPV 类型有一定关系，利用 DNA 杂交技术发现尖锐湿疣和生殖器癌组织中存在 HPV-6、11、16、18 型等。
HPV16 positive is infected with human papillomavirus. HPV can cause benign tumors and warts, such as human verruca vulgaris, condyloma acuminata and papilloma on the skin and mucosa near the reproductive organs. HPV seems to play a decisive role in skin cancer and other anatomical tumors. HPV-11, 16, 18 DNA can be found in oral benign neoplasms and precancerous lesions. In addition, there is a certain relationship between condyloma acuminatum and HPV type. Using DNA hybridization technology, we found that there are HPV-6, 11, 16, 18 types in condyloma acuminatum and genital cancer.
尖锐湿疣就诊者 HPV 亚型检测结果发现共检测出 21 种 HPV 亚型，其中 HPV16 亚型的出现率为 14.79%，位于共检测出的 21 种 HPV 亚型病毒中第三；尖锐湿疣复查患者 HPV 亚型检测后发现，共有 20 种 HPV 亚型，其中 HPV16 亚型的出现率为 17.89%，位于共检测出的 20 种 HPV 亚型病毒中第四；非尖锐湿疣就诊者 HPV 亚型检测发现，共有 17 种 HPV 亚型，其中 HPV16 亚型的出现率为 17.86%，位于共检测出的 17 种 HPV 亚型病毒中第三；尖锐湿疣患者皮损组织 HPV 亚型的检测发现，共有 21 种 HPV 亚型，其中 HPV16 亚型的出现率为 14.79%，位于高危型 HPV 亚型病毒之首。说明尖锐湿疣患者 HPV 感染以 HPV-6、11 和 16 为主要致病因子。
21 HPV subtypes were detected in patients with condyloma acuminatum, of which the incidence of HPV16 was 14.79%, which was the third of 21 HPV subtypes detected in all; after the re examination of patients with condyloma acuminatum, 20 HPV subtypes were found, of which the incidence of HPV16 subtype was 17.89%, which was located in 20 HPV subtypes detected in all There are 17 subtypes of HPV in non condyloma acuminatum patients, of which the incidence of HPV16 is 17.86%, which is the third of the 17 subtypes of HPV. There are 21 subtypes of HPV in the lesions of Condyloma Acuminatum Patients, of which the incidence of HPV16 is 14.79%, which is the high-risk type The first of the HPV subtypes. It is suggested that HPV-6, 11 and 16 are the main pathogenic factors of condyloma acuminatum infection.